The novel is structured somewhat similar to David Mitchell's Cloud Atlas. It is a collection of incidents across time, from 1760 to 2008, all linked by a certain place in the desert in Nevada. The characters are all delightfully real, and eccentric to boot. The stories range from the painfully real, to somewhat kooky. However, all enjoyable.
Clearly a work of great imagination. I actually found it much more believable and contemporary when compared to, say, Salman Rushdie's magic realism.
Won't divulge the plot too much, since a lot of the pleasure I get from the book is in the unlayering of the events that happen, without following a linear pattern. Recommend that you read the book too, and hope you enjoy it as much as I have!